Periodontal disease and atherosclerosis

How To Prevent This Gum Disease. Find Your Toothpaste Today! Increasing evidence over the past decade suggests a link between periodontal disease and atherosclerosis. The observed association of periodontal disease with atherosclerotic vascular disease , as well as evidence that periodontal disease is associated with systemic inflammation that is believed to play a role in atherosclerosis and plaque instability (7), has increased interest in using specific periodontal treatments, like mechanical debridement, to reduce the risk of atherosclerotic vascular events.

The prevalence of atherosclerosis has increased steadily due to aging population and it is one of the leading cause of mortality and morbidity worldwide. Because periodontal disease is associated with the development of atherosclerosis , it is important to understand the local immune response to P.

Innate immune players, in particular, complement and antimicrobial peptides and their effects with regard to P. Cross-reactivity between bacterial cells, including periodontal pathogens , with endothelial cells expressing HSP may explain an association between atherosclerosis and periodontal disease. The nature of inflammatory infiltrate and the presence of HSP and GroEL were examined in carotid endarterectomy specimens. Now a team of researchers has shown that a periodontal pathogen causes changes in gene expression that boost inflammation and atherosclerosis in.

A link between oral health and cardiovascular disease has been proposed for more than a century. Recently, concern about possible links between periodontal disease (PD) and atherosclerotic vascular. Periodontitis is a risk factor for heart disease.

An examination of the relation between periodontal health status and cardiovascular risk factors: serum total and HDL cholesterol, C-reactive protein, and plasma.

Richard Nagelberg discusses a recent study in the medical journal Anaerobe. The research investigated the link between eight types of periodontal bacteria and their virulence genes to atheromatous plaques in patients with ischemic heart disease. Taken together, most of the literature supports a modest association between periodontal disease and atherosclerosis.

However, data reported in several studies do not show this association. The absence of a standard definition and measures for periodontal disease complicates interpretation of , as do potential confounding risk factors common to both conditions. However, this new study merely shows an association between gum health and atherosclerosis progression. Last year, a review of 5studies published in the journal Circulation cast some doubt that gum disease actually causes heart disease.

More recently, periodontal disease (PD) has been identified as a factor related to AD. Encouraging good oral hygiene can reduce expression of inflammatory markers of AD. It is our central hypothesis that periodontal diseases, which are chronic Gramnegative infections, represent a previously unrecognized risk factor for atherosclerosis and thromboembolic events. Previous studies have demonstrated an association between periodontal disease severity and risk of coronary heart disease and stroke.

Plaque is the sticky substance that forms on your teeth soon after you have brushed. In an effort to get rid of the bacteria, the cells of your immune system release substances that inflame and damage the gums, periodontal ligament or alveolar bone. The aims of the Dental ARIC study were to determine the prevalence, extent, and severity of periodontal conditions in the dentate ARIC population and to describe the associations between those conditions and prevalent coronary heart disease , carotid artery IMT, presence of carotid artery lesions, and atherosclerosis risk factors. We hypothesize that this association may be due to an underlying inflammatory response trait, which places an individual at high risk for developing both periodontal disease and atherosclerosis.

Therefore, it is essential to clarify the relationship between periodontal disease and atherosclerosis. Substantial evidence documents an association between periodontal diseases and CV although a causal relationship has yet to be shown.

The association may be due to an underlying inflammatory response trait, which places an individual at high risk for developing both periodontal diseases and atherosclerosis. The association between periodontal disease and atherosclerotic cardiovascular disease is supported by a large body of evidence. Relationship of periodontal disease to carotid artery intima-media wall thickness: the atherosclerosis risk in communities (ARIC) study. PERIODONTAL DISEASE There are evidences that dental infection, particularly periodontal disease , is possible a risk factor for atherosclerosis coronary artery diseases.

In the oral cavity, teeth are supported by the periodontal ligament. The space between the higher point of the gingival margin and the point where the gingiva meets the dental surface is called the gingival sulcus, which is colonised with bacteria that form a biofilm or dental plaque.