Genetic gum disease

What are the stages of gum disease? Is gum disease connected to your genes? How is gum disease diagnosed? What types of diseases are the most common genetic diseases?

Current studies suggest that periodontal disease is influenced by heredity , so your genetic makeup truly does have the potential to make you more susceptible to periodontitis.

In some cases it can affect all of the teeth. TNF-α (Tumor necrosis factor-alpha) gene: TNF-α is an inflammatory cytokine involved in the body’s immune response. TNF is important to have in the right amounts.

The main cause of periodontal (gum) disease is plaque, but other factors affect the health of your gums. Studies indicate that older people have the highest rates of periodontal disease. Data from the Centers for Disease Control and Prevention indicates that over of Americans and older have periodontitis.

Studies have found that children of parents with periodontitis are more likely to have the bacteria thought to be responsible for causing plaque and eventually periodontal disease.

Studies have foun for instance, that gum disease can be more severe in people whose cells produce a cytokine ( interleukin-) that causes inflammation , which is a genetic factor. Evidence indicates that nearly one-third of Americans are predisposed to hereditary gum disease. A study in the Journal of Medical Genetics indicated that gum disease could be a genetic predisposition.

Researchers discovered that changes in a gene for the enzyme Cathepsin-C are responsible for a condition known as Papillon-Lefevre syndrome. Along with scaly and warty skin thickening and an erosion. Genetic control of periodontal disease resistance or susceptibility could be exerted through many different biologic pathways.

Another genetic study of human twins revealed significant genetic control of salivary proteins (e.g., lactoferrin , lysozyme , peroxidases , and secretory IgA ) that have important antimicrobial properties. Gum disease is an inflammation of the gum line that can progress to affect the bone that surrounds and supports your teeth. The three stages of gum disease — from least to most severe — are gingivitis , periodontitis and advanced periodontitis. Systemic conditions such as heart disease , respiratory disease , and diabetes are associated with this form of periodontitis. Periodontitis as a manifestation of systemic diseases often begins at a young age.

Necrotizing periodontal disease is an infection characterized by necrosis of gingival tissues, periodontal ligament and alveolar bone. In fact, some lifestyle factors by themselves could give you gum disease – genes or no genes. If you have a family history of gum disease , then you are more likely to have problems with your gums. This includes the two just mentioned.

Another lifestyle factor is your personal dental care.

Not brushing your teeth or flossing is a good way to get periodontal disease and a lot of cavities. Periodontal (gum) disease is an infection of the tissues that hold your teeth in place. These lesions are most commonly observed in individuals with systemic conditions such as HIV infection, malnutrition and immunosuppression.

Many genetic syndromes involve mutations of single genes or larger chromosomal regions. Periodontal ( gum ) disease , which is also known as periodontal disease , periodontitis, and pyria is a progressive disease which if left untreated may result in tooth loss. Gum disease begins with the inflammation and irritation of the gingival tissues which surround and support the teeth. Family studies suggest that susceptibility to the early onset forms of disease , particularly prepubertal and juvenile periodontitis, is, at least in part, influenced by host genotype. Inherited phagocytic cell deficiencies appear to confer risk for prepubertal periodontitis.

Periodontal disease , also known as gum disease , is a set of inflammatory conditions affecting the tissues surrounding the teeth. In its early stage, called gingivitis, the gums become swollen, re and may bleed. In its more serious form, called periodontitis, the gums can pull away from the tooth, bone can be lost, and the teeth may loosen or fall out.

Bad breath may also occur.