Lupus and periodontal disease

It is characterized by B-cell hyperactivity with an increased immunoglobulin (Ig) G production, and immune complex deposition that in connective tissue damage. What illness is similar to lupus? Recent scientific literature suggests a strong relationship between oral disease and other systemic diseases and medical conditions,” Klein says. Its origin is unknown, but factors such as smoking, hormonal changes, ultraviolet (UV) radiation and infections are possible etiologies. Periodontitis , an infectious disease that affects tissues supporting the teeth, is sparked by a change in normal mouth bacteria, triggering an inflammatory response from the immune system.

A large number of studies have shown a potential association between periodontal and autoimmune diseases , such as rheumatoid arthritis and systemic lupus erythematosus (SLE).

Similar mechanisms of tissue destruction concerning periodontitis and other autoimmune diseases have stimulated the study of a possible relationship between these conditions. Although the disease does not directly target teeth, lupus and teeth problems frequently occur together. According to the University of Maryland Medical Center, lupus is known medically as systemic lupus erythematosus , an autoimmune disease that in chronic inflammation. African American and Asian women are most at risk of developing the condition.

It has been associated with heart disease , stroke, and some cancers. Periodontal disease has some genetic qualities, and if left untreated can wreak havoc on other organs. On the other han systemic lupus erythematosus ( SLE ) is an autoimmune disease of unknown origin, which affects the connective tissue and thus various organs in the body.

The clinical manifestations of SLE vary with the severity of the disease , and its course may exhibit periods of exacerbation and remission. Learn Facts About The Difference Between Gingivitis And Periodontitis.

Its effect on oral health is the development of symptoms such as acute (sudden onset with short period of duration) or chronic( lingers for a very long period of time) soft tissue lesions. Previous evaluations suggest that there is no significant association between patients with Systemic lupus erythematosus (SLE) and Periodontitis (PD). Lupus can have an effect on oral health.

Methods: Cross-sectional study. Primary outcome was to calculate relative risk of periodontitis in participants with SLE compared to participants without SLE. Secondary outcomes were to calculate relative risk or mean difference for measures of periodontal disease. These measures of periodontal disease included P oral PI, BOP, bleeding gingival index, and CAL.

Systemic lupus erythematosus in higher prevalence and severity of periodontal disease Demographic and clinical characteristics of subjects included in the study are presented in Table 1. Sixty-seven percent of SLE patients had periodontitis, a significantly higher prevalence when compared to healthy controls (). Because lupus is an autoimmune disease that affects the collagen tissue in the entire body, the collagen component of the mucosa of the mouth, including the gingival tissue and salivary glands also present the symptoms seen elsewhere in the body. My dentist also gave something that looks like a pipe cleaner and another gadget with a rubber tip.

I have to use these everyday. A new study published in Clinical and Experimental Rheumatology links higher lupus disease activity to bacteria originating from periodontal disease. Bacterial infections are common in patients with systemic lupus erythematosus (SLE), but only recently have pathogens from the mouth been implicated as a prominent source.

Blood will be drawn form the (30) patients with SLE and will run a D-ROM test on the blood samples taken in visit and to observe the oxidative profile of the patients with SLE before and after periodontal treatment. Individuals with periodontal disease may experience bleeding of the gums when brushing, which is often the first sign of a problem. Staff at my dentist and periodontist both were quite alarmed at my having such advanced periodontal disease at this age, and they weren’t unprofessional about it but it did.

Systemic diseases such as diabetes, rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE) increase susceptibility to destructive periodontal diseases.

Other problems can also cause dry mouth, including stress, not drinking enough water, breathing through the mouth, smoking, and alcohol. As a result, the body produces antibodies that inflict cell damage, most commonly targeting joints, skin, kidneys and the nervous system.