Periodontal disease genetic

Offices Have To Say About Net32. Compares Pricing To Help You Save. How serious is periodontal gum disease? Is periodontal disease linked to other diseases? Is thalessemia a genetic disease?

For example, some people with severe periodontal disease have genetic factors that affect the immune factor interleukin-(IL-1), a cytokine involved in the inflammatory response. Genetic control of periodontal disease resistance or susceptibility could be exerted through many different biologic pathways. Another genetic study of human twins revealed significant genetic control of salivary proteins (e.g., lactoferrin, lysozyme, peroxidases, and secretory IgA) that have important antimicrobial properties.

Periodontal disease: a genetic perspective. Taba M Jr(1), Souza SL, Mariguela VC. In its early stage, called gingivitis, the gums become swollen, re and may bleed.

The genetic component plays a key role in the onset of P in fact the genetic compound can modulate the inflammation of the mucous membranes and the loss of alveolar bone.

How genetics and epigenetics link to periodontal disease : Research paper. Research indicates periodontal disease can run in families and genetic markers can now be identified. If you’ve followed excellent oral hygiene at home and maintained regular dental visits but still have serious gum (periodontal) disease, you may have a hereditary tendency toward it.

Visit the post for more. Patterns in Populations and Pedigrees. With all of the attention focused on silicon arrays, laser scanners, and the other “glamorous” gadgets of advanced genomic technologies, it is important to consider how much needs to be learned about the genetic basis of a disease before stepping into a DNA laboratory.

A study in the Journal of Medical Genetics indicated that gum disease could be a genetic predisposition. Researchers discovered that changes in a gene for the enzyme Cathepsin-C are responsible for a condition known as Papillon-Lefevre syndrome. Healthcare providers: See how amyloid deposits form and affect multiple sites in the body. Learn about this debilitating disease and how to recognize the symptoms. A review of the ge-netic background factors related to periodontal disease and the potential applications of this accumulated knowledge in the diagnosis and treat-ment of periodontal disease are included.

Tobacco users also are at increased risk for periodontal disease. Studies have shown that tobacco use may be one of the most significant risk factors in the development and progression of periodontal disease. Research has indicated that some people may be genetically susceptible to gum disease.

There are two major forms of periodontal disease : chronic and aggressive periodontitis. Briefly, periodontitis is a chronic and multifactorial polymicrobial infection initiated by the presence of bacteria, which accumulates in the gingival crevice region.

Denver, CO – Do you maintain a healthy oral care regimen, but have still found yourself being treated for gum disease ? Even patients who brush and floss, eat the right foods and maintain all appointments with their dentists may still find themselves fighting periodontal disease. Even people who are highly prone to periodontal disease because of their genetic make-up can prevent or control the disease with good oral care. Smoking and tobacco use — Smoking increases the risk of periodontal disease and the longer, and more one smokes, the higher the risk.

If periodontal disease is present, smoking makes it more severe. If you have been told you have periodontal (gum) disease , you’re not alone. These hereditary causes of gum disease involve several immune system defects that reduce the body’s ability to fight the anaerobic bacteria responsible for causing plaque and periodontal disease. Genetic causes are also linked with some rare early onset types of periodontal diseases in younger age patients with otherwise good oral health.

While microbial and other environmental factors are believed to initiate and modulate periodontal disease progression, there now exist strong supporting data that genetic polymorphisms play a role in the predisposition to and progression of periodontal diseases.